John Gray discusses his book: Venus on fire, Mars on ice. It’s also a short and uncomplicated introduction to the effects of stress on different diseases and the difference between men and women on a hormonal level with consequences for the stress response. Very clear although somewhat simplified presentation about these matters.
Amgen would like to invite healthcare professionals to visit http://angiogenesis.amgen.com, where the science of angiogenesis comes to life. Angiogenesis, a fundamental mechanism in normal development and cancer, involves multiple cellular regulators that include the angiopoietins, the VEGF family and other regulators. Amgen has developed an interactive website that will provide users with a cinematic experience through which to view the process of tumor vessel growth. This video is one of many featured on this site
Excellent video with very nice graphics. Audience’s choice for the Scientist Video Award 2009
Theres little debate that drinking moderate amounts of red wine can help the fight against heart disease, Alzheimers disease and some cancers, especially in women. The key to how much your body benefits though, is in your genes.
red wine may have health benefits
The ancient Egyptians and Greeks considered wine to be “good for health” and used it as a form of medicine. But researchers question whether this belief holds true.
What researchers have found is this: The skin and seeds of grapes may have healthy properties. A big part of this power comes from the antioxidant resveratrol. This natural plant chemical protects your cells from damage that could lead to cancer.
Red wine is full of resveratrol because it’s made from grapes. But researchers are still trying to confirm whether the resveratrol in red wine actually reduces cancer risk But if you have cancer try doing different things than drinking alcohol as this is not recommended with the therapy, Here are some things to avoid during radiation therapy.
The serving sizes for alcoholic beverages for men and women are different because women have less water in their bodies to dilute the effects of alcohol. As a result, the alcohol stays in a woman’s body longer than a man’s. And the longer large amounts of alcohol stay in your body, the higher your risk for brain and organ damage, high blood pressure and stroke .
But don’t forget, just a little bit of wine, alcohol drinking can also get out of control in some, this is also partly in your genes.
Thanks Clinical Cases and Images
On Webcinia a comprehensive an extensive resource for cancer patients and their healthcare providers is published with all the web 2.0 tools that provide support or reliable health information about cancer management
Cancer is a class of diseases resulting from uncontrolled growth of any groups of our cells. It is the 4th cause of death globally as more than 8 million people die from cancer year by year.
Be sure to check this out at Webcinia.com
On Highlight Health the cancer research blog carnival, it discusses the news from cancer research, check it out. The posts discovers basic, clinical, epidemiological and behavioral research essential to identifying causes and developing strategies for cancer prevention, diagnosis, treatment and cures.
Welcome to the 21st edition of the Cancer Research Blog Carnival, the monthly blog carnival that discusses what’s new in cancer research and includes posts covering cancer biology, cancer genetics, cancer diagnostics and cancer therapeutics. Concomitant with this edition is the start of National Cancer Research Month.
Two of three humans never get cancer. Even the majority of heavy smokers remain cancer free. Is this a matter of chance, or are there cancer-resistant genotypes?
Genetics play an important role in cancer. Not seldom the same types of cancer runs in families. Genetics tries to identify which features are inherited, and work out the details of how these features are passed from generation to generation. Genetic information is carried by a long molecule called DNA which is copied and inherited across generations.Traits are carried in DNA as instructions for constructing and operating an organism. These instructions are contained in segments of DNA called genes.
Different forms of one type of gene are called different alleles of that gene. Mutations are random events that change the sequence of a gene and therefore create a new allele. Cancer can be favored by mutations or the allelic polymorphism of many genes involved in the control of cell differentiation or division. These mutations and alleles can be part of the cause by which cells start dividing without control, even against the host of these cells, the human body. The question is whether cancer resistance is just the low occurrence of these mutations or cancer favoring alleles.
Alternative explanations for cancer resistance are:
- Cancer resistance can be induced in mouse strains. Low cancer strains can established with equal ease by selection. Besides a low tumor incidence some strains are highly resistant to most chemical carcinogenesis protocols. These strains carry multiple tumor resistance genes has been confirmed by the mapping of several loci that convey resistance at different stages of skin and lung tumor development
- Epidemiological evidence indicates that a significant proportion of the human population is highly resistant and that an equally significant fraction is highly susceptible to cancer
- Efficient immune rejection of tumors requires T-cell clones with specific receptors that can target non-self proteins. This immunological rejection is one of the mechanisms against cancer cells and viruses.
- DNA repair is a robust protection mechanism against cancer, it is also clear that there are individual variations in the efficiency of its many components.
- Both DNA damage and illegitimate activation of oncogenes can trigger apoptosis through a variety of pathways. This way “killing” activation of cancer genes and thus prevent cancer growth with Conners Clinic treatments.
- Intercellular Surveillance is a mechanism or, more appropriately, a conglomerate of mechanisms. It has been well documented, but its genetics have not been investigated. This mechanism is that normal cells could inhibit the growth of neighboring polyoma-transformed cells by direct contact. Furthermore, there is a certain ‘‘hierarchy’’ in the ability of different transformed cells to inhibit each other and to be inhibited by normal cells.These contactual interactions between normal and tumor cells may be at least partly responsible for the frequent observation that the majority of most disseminated tumor cells never grow into metastases
- A large series of somatic hybrids generated by the fusion of normal with tumor cells for tumorigenicity in vivo showed that tumor growth was suppressed with these hybrids.
The genetics of tumor resistance, responsible for the protection of the majority of individuals against cancer development, is the great terra incognita of cancer genetics
But looks promising to me, what do you think?
G. Klein (2009). Toward a genetics of cancer resistance Proceedings of the National Academy of Sciences, 106 (3), 859-863 DOI: 10.1073/pnas.0811616106
In this excellent post on Highlight HEALTH some of the secrets about genes and gliobastoma, the most common and aggressive type of brain cancer, are disclosed.
A large-scale, multi-dimensional analysis of the genomic characteristics of glioblastoma, the most common primary brain tumor in adults, provides new insights into the roles of several genes and defines core biological pathways altered in tumor development
In this search for the relation between genes and glioblastoma the Cancer Genome Atlas was used. An important collaboration.
The Cancer Genome Atlas (TCGA) is an integrated network of clinical sites, core resources and specialized genome characterization and genome sequencing centers that work together to accelerate our understanding of the molecular basis of cancer. The TCGA was launched in December 2005 as a pilot program to determine the feasibility of a large-scale effort to systematically explore genomic changes in all types of human cancer
An update on genomic changes in cancer, go read it
Only 35% of women regularly check their breasts for signs of cancer – and 23% seldom or never do, a survey suggests.
On BBC NEWS Health the charity Breakthrough Breast Cancer surveyed 2,005 women aged between 18 and 64. With the above reported results.
But is this low percentage of women checking their breasts a problem?
Not according a recent update of a Cochrane Review discussed in excellent post by Laika’s MedLibLog about The (un)usefulness of regular breast exam.
The trouble is that the Cochrane Review itself is of high quality, but two of the randomized studies included, one from Russia (1999: ~122,500 participants) and one from Shanghai (2002: ~266,000 participants) have some serious flaws. Moreover, the studies are applicable to healthy, middle-aged woman without any particular risk.
Be sure to read the post over at Laika’s blog. It contains a lot more information and discussion about breasts exam and it’s (un)usefulness.