Risperdal for Depression again Criticised

On Clinical Psychology and Psychiatry: A Closer Look another post about the ARISE-RD study, which examined Risperdal as a treatment for depression.

The letter to the editor notes many of the same concerns that I have discussed on my site, including: 1)The study reported data that was previously published, a violation of journal policy and 2) A claim regarding the drug’s efficacy was withdrawn because the statistics were done incorrectly.

On this blog I also wrote a post about a trial with risperidone for depression: Antipsychotics and Depression

If there is really an effect it is very small and clinically irrelevant. Moreover it means loosing time before using a more evidence based strategy such as lithium addition. Were looking forward for a comparison between risperidone, lithium and placebo.